Cannabinoids Explained (Part 3): Cannabigerol (CBG)

Posted on August 27 2018

cannabigerol CBG

Cannabigerol (CBG) is less popular than CBD or THC, but this cannabinoids deserves our attention as well, as studies suggest that the compound might poses some interesting properties, with potential medical applications.

CBG tends to occur in higher amounts in industrial hemp plants and in lower concentrations in the Cannabis plants grown for medical purposes. If the plant is harvested earlier, the amount of CBG present in the extracts can be higher, but the concentration of CBD and THC will be lower.

Cannabigerol is a phytocannabinoid, just like cannabidiol and THC, and is non-psychoactive, which means it does not cause one to get high. Although it occurs naturally in the cannabis plant, CBG is not produced within the human body, so it’s not part of the endocannabinoids family. What’s interesting about this compound is that cannabigerol is actually the chemical that makes the formation of CBD and THC possible.

Enzymes in the Cannabis plant convert CBG to other cannabinoids, including cannabidiol and tetrahydrocannabidiol. CBGa (CBG-acid) is the precursor of CBDa and THCa; when these acid compounds are exposed to heat or UV light for a longer period, they are converted to their neutral forms (CBD, THC).

Proven nutritive benefits of cannabigerol (CBG)

Italian researchers have studied the nutritive benefits of cannabigerol in humans, and found that it has anti-inflammatory properties. Studies about CBG have been published in journals including the Journal of Ocular Pharmacology and Therapeutics.

CBG has been classified as an antagonist of the CB1 receptor, being able to partially counteract the psychoactive effects of THC.